For analysis of QoL,
some questionnaires were prepared exclusively
for patients suffering from Parkinson’s disease (PD). The best known are two scales, Quality of Life
Questionnaire (PDQL). Martinez-Martin believes
that the quality Parkinson’s Disease. Questionnaire
(PDQ-39) and Parkinson’s Disease of life
scales are better than various other scales in
evaluating the results of rehabilitation and drug
treatment of Parkinson’s disease or neurosurgery 7. Hence, Parkinson’s
Disease Questionnaire- 39 is being used in this study.
Therefore, analysis of
the severity of any disease should include not only the clinical factors but
also the psychological & social factors pertaining with the patient.
Parkinson’s Disease has a profound negative impact on the Quality of Life (QoL)
as pointed out by numerous studies, patients suffer from fatigue, dementia,
emotional problems, sleep disorders, difficulty in speech and balance,
depression, diminished cognitive functions and several other lifestyle changes
Quality of Life (QoL) is
a multi-dimensional construct, which consists of at least three main domains:
physical, mental and social. In medicinal sciences, health-related quality of
life concept is often used by researchers and scientists. It concentrates on
the impact of the disease and/or treatment on patients’ perception of their lifestyle
and on subjective well-being or satisfaction with life 5.
Patients are usually prescribed
Levodopa, COMT Inhibitors, Dopamine Agonists, Non-Dopaminergic Therapy, etc
3. Therefore, assessing of prescriptions related to the disease is essential
to improve the therapeutic efficacy and to reduce the side effects & to
provide feedback to the prescribers. The main aim of this drug utilization
study is to facilitate rational drug use and knowing the efficacy of each one
of them 4.
The rampancy of the
disease ranges from 41 people per 100,000 in the fourth decade of life to more
than 1,900 people per 100,000 among those 80 and older 2.
Parkinson’s disease (PD)
belongs to a group of neurodegenerative conditions called motor system diseases,
which are the result of the loss of dopaminergic brain cells. The primary
symptoms of PD are tremor, or trembling in limbs, jaw, and face rigidity, or
stiffness of the limbs and slowness of trunk movement, postural instability, or
impaired balance and coordination 1.